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Ligand

NameILOPROST
Molecular formulaC22H32O4
IUPAC name(5E)-5-[(3aS,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
Molecular weight360.494
Hydrogen bond acceptor4
Hydrogen bond donor3
XlogP2.8
Synonyms(E)-(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-((E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl)-delta(sup 2(1H),delta)-pentalenevaleric acid
AN-10394
DTXSID2041046
LS-101845
Ventavis (TN)
[ Show all ]
Inchi KeyHIFJCPQKFCZDDL-SGSAMSKHSA-N
Inchi IDInChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8+/t15?,17-,18?,19-,20+,21+/m0/s1
PubChem CID6435378
ChEMBLN/A
IUPHAR1895
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 16
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
553842Prostacyclin receptorP43252PtgirMus musculus (Mouse)415
553850Prostacyclin receptorP43119PTGIRHomo sapiens (Human)386
553840Prostaglandin D2 receptorQ13258PTGDRHomo sapiens (Human)359
553843Prostaglandin E2 receptor EP1 subtypeP70597Ptger1Rattus norvegicus (Rat)405
553846Prostaglandin E2 receptor EP1 subtypeP34995PTGER1Homo sapiens (Human)402
553854Prostaglandin E2 receptor EP1 subtypeP35375Ptger1Mus musculus (Mouse)405
553844Prostaglandin E2 receptor EP2 subtypeP43116PTGER2Homo sapiens (Human)358
553848Prostaglandin E2 receptor EP2 subtypeQ62053Ptger2Mus musculus (Mouse)362
553851Prostaglandin E2 receptor EP2 subtypeQ62928Ptger2Rattus norvegicus (Rat)357
553839Prostaglandin E2 receptor EP3 subtypeP34980Ptger3Rattus norvegicus (Rat)365
553845Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
553852Prostaglandin E2 receptor EP3 subtypeP43115PTGER3Homo sapiens (Human)390
553847Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513
553849Prostaglandin E2 receptor EP4 subtypeP35408PTGER4Homo sapiens (Human)488
553853Prostaglandin F2-alpha receptorP43088PTGFRHomo sapiens (Human)359
553841Thromboxane A2 receptorP21731TBXA2RHomo sapiens (Human)343

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