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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000586692
Molecular formula	C19H16N2O6S
IUPAC name	(5Z)-3-(1,3-benzodioxol-5-yl)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-2-imino-1,3-thiazolidin-4-one
Molecular weight	400.405
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	3.4
Synonyms	AC1LO7YQ MCULE-5910288962 STK767738 (5Z)-3-(1,3-benzodioxol-5-yl)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-2-imino-1,3-thiazolidin-4-one MolPort-019-782-926 3-(2H-benzo[3,4-d]1,3-dioxolen-5-yl)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyle ne]-2-imino-1,3-thiazolidin-4-one HMS2613K23 SR-01000537905-1 (5Z)-2-azanylidene-3-(1,3-benzodioxol-5-yl)-5-[(3,5-dimethoxy-4-oxidanyl-phenyl)methylidene]-1,3-thiazolidin-4-one AKOS001728239 ZINC4577804 (5Z)-3-(1,3-benzodioxol-5-yl)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-2-imino-1,3-thiazolidin-4-one CHEMBL1428770 SMR000208071 A2765/0117248 HMS639N13 ST085545 (5Z)-3-(1,3-benzodioxol-5-yl)-5-(4-hydroxy-3,5-dimethoxy-benzylidene)-2-imino-thiazolidin-4-one BDBM50192 MolPort-002-713-961 (5Z)-3-(1,3-benzodioxol-5-yl)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-2-imino-4-thiazolidinone cid_1258954 SR-01000537905 [ Show all ]
Inchi Key	HIWBRHNPKYABSM-CQRAXGMXSA-N
Inchi ID	InChI=1S/C19H16N2O6S/c1-24-14-5-10(6-15(25-2)17(14)22)7-16-18(23)21(19(20)28-16)11-3-4-12-13(8-11)27-9-26-12/h3-8,20,22H,9H2,1-2H3/b16-7-,20-19?
PubChem CID	1258954
ChEMBL	CHEMBL1428770
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
116082	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
116083	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
116081	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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