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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N-{4-[1-benzoyl-5-(2,3-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}methanesulfonamide
Molecular formula	C25H25N3O5S
IUPAC name	N-[4-[2-benzoyl-3-(2,3-dimethoxyphenyl)-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide
Molecular weight	479.551
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.3
Synonyms	CHEMBL1609315 SCHEMBL14133446 724437-74-5 MCULE-6073062994 AP-845/42930431 N-[4-[2-benzoyl-3-(2,3-dimethoxyphenyl)-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide HMS2596J14 SMR000324576 AC1N1ADP MLS000680439 HMS3379E05 Z815263996 AKOS034603855 MolPort-002-457-597 [ Show all ]
Inchi Key	HNAOHUIEBGVNHW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H25N3O5S/c1-32-23-11-7-10-20(24(23)33-2)22-16-21(17-12-14-19(15-13-17)27-34(3,30)31)26-28(22)25(29)18-8-5-4-6-9-18/h4-15,22,27H,16H2,1-3H3
PubChem CID	4002152
ChEMBL	CHEMBL1609315
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
119174	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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