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Ligand

NameLatanoprost acid
Molecular formulaC23H34O5
IUPAC name(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid
Molecular weight390.52
Hydrogen bond acceptor5
Hydrogen bond donor4
XlogP3.1
SynonymsGTPL1960
latanoprost-free acid
SC-44791
(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoic acid
5-Heptenoic acid,7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-,(5Z)-
[ Show all ]
Inchi KeyHNPFPERDNWXAGS-NFVOFSAMSA-N
Inchi IDInChI=1S/C23H34O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,18-22,24-26H,2,7,10-16H2,(H,27,28)/b6-1-/t18-,19+,20+,21-,22+/m0/s1
PubChem CID6441636
ChEMBLCHEMBL1050
IUPHAR1960
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
119552Prostaglandin F2-alpha receptorP43117PtgfrMus musculus (Mouse)366
119553Prostaglandin F2-alpha receptorP37289PTGFRBos taurus (Bovine)362
553875Prostaglandin F2-alpha receptorP43088PTGFRHomo sapiens (Human)359

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