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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Latanoprost acid
Molecular formula	C23H34O5
IUPAC name	(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid
Molecular weight	390.52
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	3.1
Synonyms	13,14-Dihydro-17-phenyl-18,19,20-trinor-PGF2\|A CHEMBL1050 Phxa 85 Z6154 (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoic acid 5-Heptenoic acid,7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-,(5Z)- GTPL1960 latanoprost-free acid SC-44791 (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid CHEBI:63925 latanoprost (free acid form) MolPort-006-394-769 SR-01000946512-1 DTXSID6040531 Latanoprost acid, >=98% (HPLC) Phxa-85 ZINC13589951 (5Z,9alpha,11alpha,15R)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oic acid 639L832 HMS3648J04 Latanprost Free Acid SCHEMBL1313159 13,14-dihydro-17-phenyl-18,19,20-trinor-PGF2alpha Latanoprost (free acid) NCGC00165820-01 UNII-EJ85341990 (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid 41639-83-2 EJ85341990 Latanoprost Related Compound E, United States Pharmacopeia (USP) Reference Standard PHXA85 (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)-cyclopentyl)hept-5-enoic acid AC1O5VOE HNPFPERDNWXAGS-NFVOFSAMSA-N MFCD08056084 SR-01000946512 [ Show all ]
Inchi Key	HNPFPERDNWXAGS-NFVOFSAMSA-N
Inchi ID	InChI=1S/C23H34O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,18-22,24-26H,2,7,10-16H2,(H,27,28)/b6-1-/t18-,19+,20+,21-,22+/m0/s1
PubChem CID	6441636
ChEMBL	CHEMBL1050
IUPHAR	1960
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
119552	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
119553	Prostaglandin F2-alpha receptor	P37289	PTGFR	Bos taurus (Bovine)	362
553875	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359

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