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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL209754
Molecular formula	C34H35F4N5
IUPAC name	3-[4-[6-[2-(diethylamino)ethyl]-2-[5-fluoro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]-6-azaspiro[2.5]octan-2-yl]phenyl]benzonitrile
Molecular weight	589.683
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	7.1
Synonyms	BDBM50186835 4''-[6-(2-diethylamino-ethyl)-1-(5-fluoro-6-trifluoromethyl-1H-benzoimidazol-2-yl)-6-aza-spiro[2.5]oct-1-yl]-biphenyl-3-carbonitrile
Inchi Key	HTKIJSNZEHJCRA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H35F4N5/c1-3-42(4-2)16-17-43-14-12-32(13-15-43)22-33(32,26-10-8-24(9-11-26)25-7-5-6-23(18-25)21-39)31-40-29-19-27(34(36,37)38)28(35)20-30(29)41-31/h5-11,18-20H,3-4,12-17,22H2,1-2H3,(H,40,41)
PubChem CID	44413475
ChEMBL	CHEMBL209754
IUPHAR	N/A
BindingDB	50186835
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
123561	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
123560	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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