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Ligand

NameCHEMBL386320
Molecular formulaC25H24F3N3O
IUPAC name(E)-N-(4-amino-2-cyclohexylquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Molecular weight439.482
Hydrogen bond acceptor6
Hydrogen bond donor2
XlogP5.9
SynonymsBDBM50193635
SCHEMBL6202827
(E)-N-(4-amino-2-cyclohexylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
SCHEMBL6202833
Inchi KeyHUBNHNXKNZPWEP-MDWZMJQESA-N
Inchi IDInChI=1S/C25H24F3N3O/c26-25(27,28)18-9-6-16(7-10-18)8-13-24(32)30-19-11-12-22-20(14-19)21(29)15-23(31-22)17-4-2-1-3-5-17/h6-15,17H,1-5H2,(H2,29,31)(H,30,32)/b13-8+
PubChem CID10127348
ChEMBLCHEMBL386320
IUPHARN/A
BindingDB50193635
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
124131Melanin-concentrating hormone receptor 1Q99705MCHR1Homo sapiens (Human)422
124132Melanin-concentrating hormone receptor 2Q969V1MCHR2Homo sapiens (Human)340

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