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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2349324
Molecular formula	C18H22FN5OS2
IUPAC name	(2R)-2-[[2-amino-5-[(2-fluorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Molecular weight	407.526
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	4.5
Synonyms	(R)-2-[2-Amino-5-(2-fluorophenylmethylthio)-thiazolo[4,5-d]pyrimidin-7-ylamino]-4-methyl-pentan-1-ol SCHEMBL5235414 BDBM50432437 HVAOCXFQAGCNQP-GFCCVEGCSA-N
Inchi Key	HVAOCXFQAGCNQP-GFCCVEGCSA-N
Inchi ID	InChI=1S/C18H22FN5OS2/c1-10(2)7-12(8-25)21-15-14-16(22-17(20)27-14)24-18(23-15)26-9-11-5-3-4-6-13(11)19/h3-6,10,12,25H,7-9H2,1-2H3,(H3,20,21,22,23,24)/t12-/m1/s1
PubChem CID	71625272
ChEMBL	CHEMBL2349324
IUPHAR	N/A
BindingDB	50432437
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
124789	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360
124790	CX3C chemokine receptor 1	P49238	CX3CR1	Homo sapiens (Human)	355

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