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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Oxotremorine 1
Molecular formula	C11H18N2O
IUPAC name	N-methyl-N-(4-pyrrolidin-1-ylbut-2-ynyl)acetamide
Molecular weight	194.278
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	0.3
Synonyms	AC1L2EPH DTXSID90191870 N-Methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]acetamide # Acetamide, N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]- N-(4-pyrrolidino-2-butynyl) -N-methylacetamide SCHEMBL11726909 3854-05-5 N-methyl-N-(4-pyrrolidin-1-ylbut-2-ynyl)acetamide UH5;N-Methyl-N-(4-pyrrolidin-1-yl-but-2-ynyl)-acetamide ACETAMIDE, N-METHYL-N-(4-(1-PYRROLIDINYL)-2-BUTYNYL)- HWYHDWGGACRVEH-UHFFFAOYSA-N Oxo 1 BDBM50009300 N-Methyl-N-(4-pyrrolidin-1'-ylbut-2-ynyl)acetamide UH 5 CHEMBL11081 N-methyl-N-(4-pyrrolidino-2-butynyl)acetamide Acetamide, N-methyl-N-[4-(1-pyrrolidinyl)-2-butyn-1-yl]- LS-10001 BRN 4247641 N-Methyl-N-(4-pyrrolidin-1-yl-but-2-ynyl)-acetamide UH-5 [ Show all ]
Inchi Key	HWYHDWGGACRVEH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H18N2O/c1-11(14)12(2)7-3-4-8-13-9-5-6-10-13/h5-10H2,1-2H3
PubChem CID	19716
ChEMBL	CHEMBL11081
IUPHAR	N/A
BindingDB	50009300
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
125949	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
125946	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
125945	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
125947	Muscarinic acetylcholine receptor M3	Q9ERZ3	Chrm3	Mus musculus (Mouse)	589
125948	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
125944	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478

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