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Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	139290-69-0
Molecular formula	C22H28FNO3
IUPAC name	(2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol
Molecular weight	373.468
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.9
Synonyms	alpha-[1-[2-(4-Fluorophenyl)ethyl]piperidine-4-yl]-2,3-dimethoxybenzyl alcohol L001296 PDSP1_001496 (2,3-dimethoxy-phenyl)-{1-[2-(4-fluorophenyl)-ethyl}-piperidin-4-yl}-methanol (2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol AC1Q4NRW BW A360C MDL 100105 racemic alpha(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol D03QNE MDL100105 SCHEMBL340674 (+/-)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol AN-5556 LS-115604 PDSP2_001480 (2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol (2,3-dimethoxyphenyl){1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl}methanol AKOS027338720 C22H28FNO3 MDL 100151 racemic alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol (+/-)-ALPHA-(2,3-DIMETHOXY-PHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINE-METHANOL 4-Piperidinemethanol, alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-, (+)- alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]4-piperidine methanol HXTGXYRHXAGCFP-UHFFFAOYSA-N MolPort-039-331-873 (1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol AC1L1U2G BDBM50232153 Mdl 100,907 racemic alpha(2,3-dimethoxyphenyl)- 1 -[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol (2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]-4-piperidyl]methanol alpha-(2,3-Dimethoxyphenyl)-1-(2-(4-fluorophenylethyl))-4-piperidine methanol CHEMBL257283 MDL 100907, (+/-)- SCHEMBL13701277 (+/-)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)-ethyl]-4-piperidinemethanol [ Show all ]
Inchi Key	HXTGXYRHXAGCFP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3
PubChem CID	60858
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50232153
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
126675	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
126666	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
126671	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
126657	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
555984	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
126665	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
126656	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
126661	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
126653	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
126648	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
126649	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
126678	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
126660	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
126667	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
126654	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
126664	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
126677	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
460382	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
126668	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
126655	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477