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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL61681
Molecular formula	C27H28N4O2
IUPAC name	(2S)-2-(benzylcarbamoylamino)-3-(1H-indol-3-yl)-N-[(3-methylphenyl)methyl]propanamide
Molecular weight	440.547
Hydrogen bond acceptor	2
Hydrogen bond donor	4
XlogP	4.0
Synonyms	2-(3-Benzyl-ureido)-3-(1H-indol-3-yl)-N-(3-methyl-benzyl)-propionamide BDBM50129183
Inchi Key	IBFSTESMBHZKAL-VWLOTQADSA-N
Inchi ID	InChI=1S/C27H28N4O2/c1-19-8-7-11-21(14-19)17-29-26(32)25(15-22-18-28-24-13-6-5-12-23(22)24)31-27(33)30-16-20-9-3-2-4-10-20/h2-14,18,25,28H,15-17H2,1H3,(H,29,32)(H2,30,31,33)/t25-/m0/s1
PubChem CID	44305815
ChEMBL	CHEMBL61681
IUPHAR	N/A
BindingDB	50129183
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
129055	Melanocortin receptor 3	P33033	Mc3r	Mus musculus (Mouse)	323
129054	Melanocortin receptor 4	P56450	Mc4r	Mus musculus (Mouse)	332
129056	Melanocortin receptor 5	P41149	Mc5r	Mus musculus (Mouse)	325
129057	Melanocyte-stimulating hormone receptor	Q01727	Mc1r	Mus musculus (Mouse)	315

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