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Ligand

NameCHEMBL1813118
Molecular formulaC28H25FN2O5
IUPAC name2-[5-fluoro-2-methyl-1-[4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]indol-3-yl]acetic acid
Molecular weight488.515
Hydrogen bond acceptor7
Hydrogen bond donor1
XlogP5.4
SynonymsBDBM50350369
SCHEMBL5647327
Inchi KeyIIWBXJIMFARCEB-NRFANRHFSA-N
Inchi IDInChI=1S/C28H25FN2O5/c1-17-22(14-27(32)33)23-13-19(29)9-12-24(23)31(17)28(34)18-7-10-20(11-8-18)35-16-21-15-30(2)25-5-3-4-6-26(25)36-21/h3-13,21H,14-16H2,1-2H3,(H,32,33)/t21-/m0/s1
PubChem CID10228100
ChEMBLCHEMBL1813118
IUPHARN/A
BindingDB50350369
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
134269Prostacyclin receptorP43119PTGIRHomo sapiens (Human)386
134263Prostaglandin D2 receptorP70263PtgdrMus musculus (Mouse)357
134270Prostaglandin E2 receptor EP1 subtypeP35375Ptger1Mus musculus (Mouse)405
134267Prostaglandin E2 receptor EP2 subtypeQ62053Ptger2Mus musculus (Mouse)362
134264Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
134266Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513
134265Prostaglandin F2-alpha receptorP43117PtgfrMus musculus (Mouse)366
134268Thromboxane A2 receptorP21731TBXA2RHomo sapiens (Human)343

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