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Ligand

NameCHEMBL377372
Molecular formulaC30H25F4N5
IUPAC name5-[4-[[1-(cyclopropylmethyl)piperidin-4-ylidene]-[5-fluoro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]methyl]phenyl]pyridine-3-carbonitrile
Molecular weight531.559
Hydrogen bond acceptor8
Hydrogen bond donor1
XlogP6.0
SynonymsBDBM50186849
5-{4-[(1-cyclopropylmethyl-piperidin-4-ylidene)-(5-fluoro-6-trifluoromethyl-1H-benzoimidazol-2-yl)-methyl]-phenyl}-nicotinonitrile
Inchi KeyIJJCMSQNNRCBFX-UHFFFAOYSA-N
Inchi IDInChI=1S/C30H25F4N5/c31-25-13-27-26(12-24(25)30(32,33)34)37-29(38-27)28(22-7-9-39(10-8-22)17-18-1-2-18)21-5-3-20(4-6-21)23-11-19(14-35)15-36-16-23/h3-6,11-13,15-16,18H,1-2,7-10,17H2,(H,37,38)
PubChem CID44413297
ChEMBLCHEMBL377372
IUPHARN/A
BindingDB50186849
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
134631Melanin-concentrating hormone receptor 1Q99705MCHR1Homo sapiens (Human)422
134632Melanin-concentrating hormone receptor 2Q969V1MCHR2Homo sapiens (Human)340

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