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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL63063
Molecular formula	C22H26N2O2
IUPAC name	5,6-dimethoxy-11-methyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaene
Molecular weight	350.462
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.3
Synonyms	2,3-dimethoxy-7-methyl-6,7,8,9,14,15-hexahydro-5H-benzo[7,8]azecino[5,4-b]indole BDBM50088340
Inchi Key	ILLDXVCWSLGVJR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26N2O2/c1-24-10-8-15-13-21(25-2)22(26-3)14-16(15)12-20-18(9-11-24)17-6-4-5-7-19(17)23-20/h4-7,13-14,23H,8-12H2,1-3H3
PubChem CID	10807793
ChEMBL	CHEMBL63063
IUPHAR	N/A
BindingDB	50088340
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
136080	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
447051	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
136082	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
136083	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
136078	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
136079	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
136081	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460

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