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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AH23848
Molecular formula	C29H35NO5
IUPAC name	(Z)-7-[(1R,2R,5S)-2-morpholin-4-yl-3-oxo-5-[(4-phenylphenyl)methoxy]cyclopentyl]hept-4-enoic acid
Molecular weight	477.601
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	1.6
Synonyms	(Z)-7-[(1R,2R,5S)-2-morpholin-4-yl-3-oxo-5-[(4-phenylphenyl)methoxy]cyclopentyl]hept-4-enoic acid CHEBI:90389 (-)-AH 23848 AC1NSJSW SCHEMBL3488581 (1R,2R,5S)-AH23848 AH-23848B (Z)-7-[5alpha-(1,1'-Biphenyl-4-ylmethoxy)-2beta-(4-morpholinyl)-3-oxocyclopentan-1alpha-yl]-4-heptenoic acid D07WQV (-)-AH23848 AH 23848 UNII-9NEV21ZEL6 component IOFUFYLETVNNRF-OSAZKUMMSA-N (4Z)-7-[(1R,2R,5S)-5-[([1,1'-biphenyl]-4-yl)methoxy]-2-(morpholin-4-yl)-3-oxocyclopentyl]hept-4-enoic acid GTPL1949 (-)AH23848 AH-23848 ZINC33359821 [ Show all ]
Inchi Key	IOFUFYLETVNNRF-OSAZKUMMSA-N
Inchi ID	InChI=1S/C29H35NO5/c31-26-20-27(35-21-22-12-14-24(15-13-22)23-8-4-3-5-9-23)25(10-6-1-2-7-11-28(32)33)29(26)30-16-18-34-19-17-30/h1-5,8-9,12-15,25,27,29H,6-7,10-11,16-21H2,(H,32,33)/b2-1-/t25-,27-,29+/m0/s1
PubChem CID	5310999
ChEMBL	N/A
IUPHAR	1949
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553977	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
553978	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488
553979	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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