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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL216428
Molecular formula	C24H24F3N3O
IUPAC name	(E)-N-(4-amino-2-pentylquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Molecular weight	427.471
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.9
Synonyms	BDBM50193605 SCHEMBL6201704 (E)-N-(4-amino-2-pentylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide SCHEMBL6201710
Inchi Key	IQVXYTILPWMXFT-MDWZMJQESA-N
Inchi ID	InChI=1S/C24H24F3N3O/c1-2-3-4-5-18-15-21(28)20-14-19(11-12-22(20)29-18)30-23(31)13-8-16-6-9-17(10-7-16)24(25,26)27/h6-15H,2-5H2,1H3,(H2,28,29)(H,30,31)/b13-8+
PubChem CID	44417959
ChEMBL	CHEMBL216428
IUPHAR	N/A
BindingDB	50193605
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
139693	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
139692	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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