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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BRD-A72341983-001-05-8
Molecular formula	C19H23ClN4O5S2
IUPAC name	5-chloro-N-[4-(2-ethylpiperidin-1-yl)sulfonylphenyl]-2-methylsulfonylpyrimidine-4-carboxamide
Molecular weight	486.986
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	2.5
Synonyms	AKOS001514873 MLS001116347 5-chloro-N-[4-(2-ethylpiperidin-1-yl)sulfonylphenyl]-2-methylsulfonylpyrimidine-4-carboxamide REGID_for_CID_16437205 5-chloro-N-{4-[(2-ethylpiperidin-1-yl)sulfonyl]phenyl}-2-(methylsulfonyl)pyrimidine-4-carboxamide cid_16437205 SR-01000823836-2 AKOS016160377 MLS003880620 5-chloro-N-[4-(2-ethylpiperidino)sulfonylphenyl]-2-mesyl-pyrimidine-4-carboxamide SMR000625579 MCULE-1811395225 STK908417 5-chloranyl-N-[4-(2-ethylpiperidin-1-yl)sulfonylphenyl]-2-methylsulfonyl-pyrimidine-4-carboxamide BDBM54849 MolPort-000-399-293 5-chloro-N-[4-[(2-ethyl-1-piperidinyl)sulfonyl]phenyl]-2-methylsulfonyl-4-pyrimidinecarboxamide CHEMBL1407961 SR-01000823836 [ Show all ]
Inchi Key	ISAAEPNCJSJWPZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H23ClN4O5S2/c1-3-14-6-4-5-11-24(14)31(28,29)15-9-7-13(8-10-15)22-18(25)17-16(20)12-21-19(23-17)30(2,26)27/h7-10,12,14H,3-6,11H2,1-2H3,(H,22,25)
PubChem CID	16437205
ChEMBL	CHEMBL1407961
IUPHAR	N/A
BindingDB	54849
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
140519	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
140520	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
140518	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
140523	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
140522	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
480233	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
140521	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764
140524	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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