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Ligand

Namemetoprolol
Molecular formulaC15H25NO3
IUPAC name1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
Molecular weight267.369
Hydrogen bond acceptor4
Hydrogen bond donor2
XlogP1.9
Synonyms2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-
IUBSYMUCCVWXPE-UHFFFAOYSA-N
Lopresor
AC-19022
LS-122450
[ Show all ]
Inchi KeyIUBSYMUCCVWXPE-UHFFFAOYSA-N
Inchi IDInChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3
PubChem CID4171
ChEMBLCHEMBL13
IUPHAR553
BindingDB25756
DrugBankDB00264

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 11
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1418235-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
1418255-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
141816Beta-1 adrenergic receptorP18090Adrb1Rattus norvegicus (Rat)466
141817Beta-1 adrenergic receptorP08588ADRB1Homo sapiens (Human)477
141818Beta-2 adrenergic receptorP07550ADRB2Homo sapiens (Human)413
141821Beta-2 adrenergic receptorQ8K4Z4Adrb2Cavia porcellus (Guinea pig)418
141824Beta-2 adrenergic receptorP54833ADRB2Canis lupus familiaris (Dog)415
460508Beta-2 adrenergic receptorP10608Adrb2Rattus norvegicus (Rat)418
141822Beta-3 adrenergic receptorP13945ADRB3Homo sapiens (Human)408
141820Neuropeptide Y receptor type 1P25929NPY1RHomo sapiens (Human)384
141819Neuropeptide Y receptor type 2P49146NPY2RHomo sapiens (Human)381

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