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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	LEVOBUNOLOL
Molecular formula	C17H25NO3
IUPAC name	5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one
Molecular weight	291.391
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.4
Synonyms	(S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-3,4-dihydronaphthalen-1(2H)-one AC1Q6JRH beta-site CAS-27912-14-7 D08115 KB-211580 liquifilm Prestwick2_000847 W-7000A 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalen-1-one AK-Beta (TN) BPBio1_000917 CCRIS 4375 DTXSID1043833 Levobunolol (INN) NCGC00016801-01 SPBio_002754 (-)-Bunolol API0003156 C-18293 CHEMBL1201237 GTPL570 Levobunololum Prestwick0_000847 W-6412A 1(2H)-Naphthalenone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-, (S)- AJ-45756 Betagan CAS-47141-41-3 l-Bunolol Liquifilm (TN) Prestwick3_000847 ZINC3830339 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one Akbeta BRD-K31812033-003-03-7 CHEBI:6438 FT-0604397 Levobunolol HCl NCGC00016801-02 UNII-71QSY2UT3G component IXHBTMCLRNMKHZ-LBPRGKRZSA-N (S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenone AC1L21RP AX8246776 C07914 D00IUG IXHBTMCLRNMKHZ-LBPRGKRZSA-N Levobunololum [INN-Latin] Prestwick1_000847 W-6421A 47141-42-4 Ak-beta Betegan (TN) CC-29916 DB01210 LS-175034 SCHEMBL24095 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one AKOS016012242 BSPBio_000833 G6317AOI7K Levobunolol [INN:BAN] NCGC00016801-03 UNII-G6317AOI7K [ Show all ]
Inchi Key	IXHBTMCLRNMKHZ-LBPRGKRZSA-N
Inchi ID	InChI=1S/C17H25NO3/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3/t12-/m0/s1
PubChem CID	39468
ChEMBL	CHEMBL1201237
IUPHAR	570
BindingDB	N/A
DrugBank	DB01210
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
143988	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
143986	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
143987	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
143982	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
553997	Beta-3 adrenergic receptor	P25962	Adrb3	Mus musculus (Mouse)	400
553998	Beta-3 adrenergic receptor	P26255	Adrb3	Rattus norvegicus (Rat)	400
143983	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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