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Ligand

Nametolazoline
Molecular formulaC10H12N2
IUPAC name2-benzyl-4,5-dihydro-1H-imidazole
Molecular weight160.22
Hydrogen bond acceptor1
Hydrogen bond donor1
XlogP2.6
Synonyms1H-Imidazole, 4,5-dihydro-2-(phenylmethyl)-
JIVZKJJQOZQXQB-UHFFFAOYSA-N
2-benzyl-2-imidazoline;hydrochloride
KBioGR_000793
2-IMIDAZOLINE, 2-BENZYL-
[ Show all ]
Inchi KeyJIVZKJJQOZQXQB-UHFFFAOYSA-N
Inchi IDInChI=1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12)
PubChem CID5504
ChEMBLCHEMBL770
IUPHAR7310
BindingDB55436
DrugBankDB00797

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 14
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1520055-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
1520005-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
5560505-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
152006Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
152007Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
151998Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
152001Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
152004Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
151996Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
152002Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
152003Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
152008Histamine H2 receptorP25021HRH2Homo sapiens (Human)359
151999Thyrotropin receptorP16473TSHRHomo sapiens (Human)764
151997Trace amine-associated receptor 1Q96RJ0TAAR1Homo sapiens (Human)339

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