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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL390290
Molecular formula	C25H29ClFN3O2S
IUPAC name	1-[4-(5-acetylthiophen-2-yl)cyclohex-3-en-1-yl]-3-(3-chloro-4-fluorophenyl)-1-(2-pyrrolidin-1-ylethyl)urea
Molecular weight	490.034
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.9
Synonyms	BDBM50215621 1-(4-(5-acetylthiophen-2-yl)cyclohex-3-enyl)-3-(3-chloro-4-fluorophenyl)-1-(2-(pyrrolidin-1-yl)ethyl)urea
Inchi Key	JPJRQKREDRIUHQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H29ClFN3O2S/c1-17(31)23-10-11-24(33-23)18-4-7-20(8-5-18)30(15-14-29-12-2-3-13-29)25(32)28-19-6-9-22(27)21(26)16-19/h4,6,9-11,16,20H,2-3,5,7-8,12-15H2,1H3,(H,28,32)
PubChem CID	44424268
ChEMBL	CHEMBL390290
IUPHAR	N/A
BindingDB	50215621
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
156600	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
156601	Melanin-concentrating hormone receptor 1	Q8JZL2	Mchr1	Mus musculus (Mouse)	353

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