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Ligand

NameMK-912
Molecular formulaC20H25N3O2
IUPAC name1',3'-dimethylspiro[1,3,4,6,7,12b-hexahydro-[1]benzofuro[2,3-a]quinolizine-2,4'-1,3-diazinane]-2'-one
Molecular weight339.439
Hydrogen bond acceptor3
Hydrogen bond donor0
XlogP2.3
SynonymsAC1L3X3J
L 657743
CCG-204845
L023963
NCGC00162243-01
[ Show all ]
Inchi KeyJRDUBBHIPPPSLP-UHFFFAOYSA-N
Inchi IDInChI=1S/C20H25N3O2/c1-21-11-8-20(22(2)19(21)24)9-12-23-10-7-15-14-5-3-4-6-17(14)25-18(15)16(23)13-20/h3-6,16H,7-13H2,1-2H3
PubChem CID123679
ChEMBLCHEMBL1256985
IUPHARN/A
BindingDB81811
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
157921Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
157919Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
460645Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
157922Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
157920D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446

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