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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL495736
Molecular formula	C28H36ClN5O3
IUPAC name	[1-[1-[4-[(4-chlorophenyl)methylamino]-6,7-dimethoxyquinazolin-2-yl]piperidin-4-yl]piperidin-3-yl]methanol
Molecular weight	526.078
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.0
Synonyms	BDBM50265748 (1''-{4-[(4-Chlorobenzyl)amino]-6,7-dimethoxyquinazolin-2-yl}-1,4''-bipiperidin-3-yl)methanol
Inchi Key	JUTQNVZXCFFRSI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H36ClN5O3/c1-36-25-14-23-24(15-26(25)37-2)31-28(32-27(23)30-16-19-5-7-21(29)8-6-19)33-12-9-22(10-13-33)34-11-3-4-20(17-34)18-35/h5-8,14-15,20,22,35H,3-4,9-13,16-18H2,1-2H3,(H,30,31,32)
PubChem CID	44581102
ChEMBL	CHEMBL495736
IUPHAR	N/A
BindingDB	50265748
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
160483	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360
160484	C-C chemokine receptor type 4	P51680	Ccr4	Mus musculus (Mouse)	360

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