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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431131
Molecular formula	C23H25ClN4O2
IUPAC name	4-[4-(2-chlorophenyl)piperazin-1-yl]-2-cyclopropyl-6,7-dimethoxyquinazoline
Molecular weight	424.929
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.7
Synonyms	BDBM50440762 MLS-0471515.0001 SCHEMBL15818963
Inchi Key	KMQHCXSTAQSUDR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25ClN4O2/c1-29-20-13-16-18(14-21(20)30-2)25-22(15-7-8-15)26-23(16)28-11-9-27(10-12-28)19-6-4-3-5-17(19)24/h3-6,13-15H,7-12H2,1-2H3
PubChem CID	56593272
ChEMBL	CHEMBL2431131
IUPHAR	N/A
BindingDB	50440762
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
172913	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
172912	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
172914	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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