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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3963788
Molecular formula	C17H16F2N4O3S2
IUPAC name	5-amino-N-[[4-(difluoromethylsulfonyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide
Molecular weight	426.457
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	3.1
Synonyms	BDBM50207463 KNZAIFIZJGFOCI-UHFFFAOYSA-N 5-amino-N-(4-((difluoromethyl)sulfonyl)benzyl)-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide SCHEMBL15212221
Inchi Key	KNZAIFIZJGFOCI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H16F2N4O3S2/c1-8-9(2)22-23-16-12(8)13(20)14(27-16)15(24)21-7-10-3-5-11(6-4-10)28(25,26)17(18)19/h3-6,17H,7,20H2,1-2H3,(H,21,24)
PubChem CID	89768534
ChEMBL	CHEMBL3963788
IUPHAR	N/A
BindingDB	50207463
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
540451	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
540456	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
540452	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
540454	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
540450	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
540453	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
540449	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
540455	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
540457	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531
540458	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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