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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL273921
Molecular formula	C24H27FN4O2
IUPAC name	2-[2-[4-(5-fluoro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-4,5-dihydro-3H-2-benzazepin-1-one
Molecular weight	422.504
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.0
Synonyms	2-[2-[4-(5-fluoro-2-oxo-2,3-dihydro-1h-benzimidazol-1-yl)piperidin-1-yl]ethyl]-2,3,4,5-tetrahydro-1h-2-benzazepin-1-one BDBM50125260 2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-ethyl}-2,3,4,5-tetrahydro-benzo[c]azepin-1-one 2-[2-[4-(2-Oxo-5-fluoro-2,3-dihydro-1H-benzimidazole-1-yl)piperidino]ethyl]-2,3,4,5-tetrahydro-1H-2-benzazepine-1-one
Inchi Key	KOTITFQGTVUMBT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27FN4O2/c25-18-7-8-22-21(16-18)26-24(31)29(22)19-9-12-27(13-10-19)14-15-28-11-3-5-17-4-1-2-6-20(17)23(28)30/h1-2,4,6-8,16,19H,3,5,9-15H2,(H,26,31)
PubChem CID	9888494
ChEMBL	CHEMBL273921
IUPHAR	N/A
BindingDB	50125260
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
174367	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
174370	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
174366	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
174375	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
174369	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
174364	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
174374	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
174377	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
174365	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
174373	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
174372	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
174371	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
174376	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
174363	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
174378	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
174379	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
174368	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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