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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL124208
Molecular formula	C24H26FN3O2
IUPAC name	3-benzyl-8-[2-(5-fluoro-1H-indol-3-yl)ethyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Molecular weight	407.489
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.0
Synonyms	8-[2-(5-Fluoro-1H-indol-3-yl)ethyl]-3-benzyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one SCHEMBL13864782
Inchi Key	KSQAOYHTDJHQEM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26FN3O2/c25-20-6-7-22-21(14-20)19(15-26-22)8-11-27-12-9-24(10-13-27)17-28(23(29)30-24)16-18-4-2-1-3-5-18/h1-7,14-15,26H,8-13,16-17H2
PubChem CID	9887650
ChEMBL	CHEMBL124208
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
177259	Neuromedin-K receptor	P30098	TACR3	Cavia porcellus (Guinea pig)	440
177258	Substance-K receptor	P16610	Tacr2	Rattus norvegicus (Rat)	390
177260	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
177261	Substance-K receptor	Q64077	TACR2	Cavia porcellus (Guinea pig)	402
177262	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407
177263	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407

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