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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL460827
Molecular formula	C18H21FN4O2
IUPAC name	tert-butyl 4-[1-(4-fluorophenyl)triazol-4-yl]-3,6-dihydro-2H-pyridine-1-carboxylate
Molecular weight	344.39
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.5
Synonyms	tert-Butyl 4-[1-(4-fluorophenyl)-1H-[1,2,3]triazol-4-yl]-1,2,3,6-tetrahydropyridine-1-carboxylate BDBM50273863 KSSMUDDDTIMETC-UHFFFAOYSA-N tert-Butyl-4-[1-(4-fuluorophenyl)-1H-1,2,3-triazol-4-yl]-3,6-dihydropyridine-1(2H)-carboxylate SCHEMBL2892824
Inchi Key	KSSMUDDDTIMETC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H21FN4O2/c1-18(2,3)25-17(24)22-10-8-13(9-11-22)16-12-23(21-20-16)15-6-4-14(19)5-7-15/h4-8,12H,9-11H2,1-3H3
PubChem CID	44588425
ChEMBL	CHEMBL460827
IUPHAR	N/A
BindingDB	50273863
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
177343	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
177344	Metabotropic glutamate receptor 1	P97772	Grm1	Mus musculus (Mouse)	1199
177345	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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