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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL52485
Molecular formula	C24H36N2O4
IUPAC name	1-[4-[(5-methoxy-3,4-dihydro-2H-chromen-3-yl)-propylamino]butyl]-4,4-dimethylpiperidine-2,6-dione
Molecular weight	416.562
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.7
Synonyms	BDBM50036849 5-Methoxy-3-{N-propyl-N[4-(4,4-dimethyl-2,6-dioxo-1-piperidyl)butyl]amino}chroman SCHEMBL9306008 1-[4-[[(5-Methoxy-3,4-dihydro-2H-1-benzopyran)-3-yl]propylamino]butyl]-4,4-dimethylpiperidine-2,6-dione KZRCUUSRYFALEA-UHFFFAOYSA-N CHEMBL26975 1-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl}-4,4-dimethyl-piperidine-2,6-dione; compound with oxalic acid LS-115210 [ Show all ]
Inchi Key	KZRCUUSRYFALEA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H36N2O4/c1-5-11-25(18-14-19-20(29-4)9-8-10-21(19)30-17-18)12-6-7-13-26-22(27)15-24(2,3)16-23(26)28/h8-10,18H,5-7,11-17H2,1-4H3
PubChem CID	10024943
ChEMBL	CHEMBL26975
IUPHAR	N/A
BindingDB	50036849
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
182090	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
182089	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
182093	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
182091	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
182094	Alpha-2A adrenergic receptor	Q28838	ADRA2A	Bos taurus (Bovine)	452
182088	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
182092	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444

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