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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3290737
Molecular formula	C33H33ClN4O6
IUPAC name	ethyl 2-[3-[5-chloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-3-methyl-1-benzofuran-2-yl]propanoylamino]acetate
Molecular weight	617.099
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	5.1
Synonyms	BDBM50019465
Inchi Key	LCPHXJRRBBZJNX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H33ClN4O6/c1-3-42-30(40)19-36-29(39)13-12-26-20(2)31-28(43-26)11-10-23(34)32(31)44-27-14-15-35-18-22(27)33(41)38-17-16-37(21-8-9-21)24-6-4-5-7-25(24)38/h4-7,10-11,14-15,18,21H,3,8-9,12-13,16-17,19H2,1-2H3,(H,36,39)
PubChem CID	90644447
ChEMBL	CHEMBL3290737
IUPHAR	N/A
BindingDB	50019465
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
184153	G-protein coupled bile acid receptor 1	Q8TDU6	GPBAR1	Homo sapiens (Human)	330
184154	G-protein coupled bile acid receptor 1	Q80SS6	Gpbar1	Mus musculus (Mouse)	329

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