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Ligand

NameMLS001116168
Molecular formulaC19H15ClFN3O3S
IUPAC name5-chloro-N-(4-fluorophenyl)-2-[(2-methylphenyl)methylsulfonyl]pyrimidine-4-carboxamide
Molecular weight419.855
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP3.5
SynonymsAKOS001523551
5-chloro-N-(4-fluorophenyl)-2-(2-methylbenzyl)sulfonyl-pyrimidine-4-carboxamide
CHEMBL1477528
STK517433
5-chloro-N-(4-fluorophenyl)-2-[(2-methylphenyl)methylsulfonyl]pyrimidine-4-carboxamide
[ Show all ]
Inchi KeyLIEQNFQFBUWUFS-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H15ClFN3O3S/c1-12-4-2-3-5-13(12)11-28(26,27)19-22-10-16(20)17(24-19)18(25)23-15-8-6-14(21)7-9-15/h2-10H,11H2,1H3,(H,23,25)
PubChem CID16452954
ChEMBLCHEMBL1477528
IUPHARN/A
BindingDB54506
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
188131Apelin receptorP35414APLNRHomo sapiens (Human)380
188128C-C chemokine receptor type 6P51684CCR6Homo sapiens (Human)374
188129C-X-C chemokine receptor type 5P32302CXCR5Homo sapiens (Human)372
188130Glucagon-like peptide 1 receptorP43220GLP1RHomo sapiens (Human)463
188127Lutropin-choriogonadotropic hormone receptorP22888LHCGRHomo sapiens (Human)699
188126Thyrotropin receptorP16473TSHRHomo sapiens (Human)764

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