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Ligand

NameHYDROCODONE
Molecular formulaC18H21NO3
IUPAC name(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular weight299.37
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP2.2
SynonymsZINC1280665
DEA No. 9193
GTPL7081
Hydrocodon
Hydrocodone prodrug (Bio-MD/immediate release, pain), PharmacoFore
[ Show all ]
Inchi KeyLLPOLZWFYMWNKH-CMKMFDCUSA-N
Inchi IDInChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1
PubChem CID5284569
ChEMBLCHEMBL1457
IUPHAR7081
BindingDB50386689
DrugBankDB00956

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 4
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
190507Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
190508Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
526973Mas-related G-protein coupled receptor member X2Q96LB1MRGPRX2Homo sapiens (Human)330
190506Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400

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