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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	AM095 free acid
Molecular formula	C27H24N2O5
IUPAC name	2-[4-[4-[3-methyl-4-[[(1R)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]acetic acid
Molecular weight	456.498
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.0
Synonyms	EX-A1955 NCGC00378906-02 AM-095 KB-63701 ZINC68247723 2-[4-[4-[3-methyl-4-[[(1R)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]acetic acid AM-152) D06XGC Lysophosphatidic acid antagonists (fibrotic disease), Amira {4'-[3-Methyl-4-({[(1R)-1-phenylethoxy]carbonyl}amino)-1,2-oxazol-5-yl][1,1'-biphenyl]-4-yl}acetic acid AKOS030525392 BCP09983 GTPL6988 SCHEMBL2288084 1228690-36-5 AM-095 (free base) CHEMBL2182052 LNDDRUPAICPXIN-GOSISDBHSA-N [1,1'-Biphenyl]-4acetic acid,4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl]- AM095 (free acid) DTXSID10673108 MolPort-042-665-859 AM 095 BDBM50398127 HY-16040 W-5973 2-(4-{4-[3-methyl-4-({[(1R)-1-phenylethoxy]carbonyl}amino)-1,2-oxazol-5-yl]phenyl}phenyl)acetic acid AM-095 free acid CS-1129 LPA1 antagonists (fibrotic disease), Amira {4'-[3-Methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl}-acetic acid [ Show all ]
Inchi Key	LNDDRUPAICPXIN-GOSISDBHSA-N
Inchi ID	InChI=1S/C27H24N2O5/c1-17-25(28-27(32)33-18(2)20-6-4-3-5-7-20)26(34-29-17)23-14-12-22(13-15-23)21-10-8-19(9-11-21)16-24(30)31/h3-15,18H,16H2,1-2H3,(H,28,32)(H,30,31)/t18-/m1/s1
PubChem CID	46213949
ChEMBL	CHEMBL2182052
IUPHAR	6988
BindingDB	50398127
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
191496	Lysophosphatidic acid receptor 1	Q92633	LPAR1	Homo sapiens (Human)	364
554229	Lysophosphatidic acid receptor 1	P61793	Lpar1	Mus musculus (Mouse)	364
486637	Lysophosphatidic acid receptor 2	Q9HBW0	LPAR2	Homo sapiens (Human)	351
486638	Lysophosphatidic acid receptor 3	Q9UBY5	LPAR3	Homo sapiens (Human)	353
486636	Lysophosphatidic acid receptor 4	Q99677	LPAR4	Homo sapiens (Human)	370
486635	Lysophosphatidic acid receptor 5	Q9H1C0	LPAR5	Homo sapiens (Human)	372

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