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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ONO-8713
Molecular formula	C25H24F3NO6S
IUPAC name	(E)-3-[4-[[2-[furan-2-ylsulfonyl(2-methylpropyl)amino]-5-(trifluoromethyl)phenoxy]methyl]phenyl]prop-2-enoic acid
Molecular weight	523.523
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	5.7
Synonyms	ONO 8713 GTPL1921 4-[2-[N-isobutyl-N-(2-furylsulfonyl)amino]-5-trifluoromethylphenoxy-methyl]cinnamic acid LS-123647 (E)-3-[4-[[2-(furan-2-ylsulfonyl-(2-methylpropyl)amino)-5-(trifluoromethyl)phenoxy]methyl]phenyl]prop-2-enoic acid ONO8713 D0T2GA [ Show all ]
Inchi Key	LOQMSUDLLHPPHQ-FMIVXFBMSA-N
Inchi ID	InChI=1S/C25H24F3NO6S/c1-17(2)15-29(36(32,33)24-4-3-13-34-24)21-11-10-20(25(26,27)28)14-22(21)35-16-19-7-5-18(6-8-19)9-12-23(30)31/h3-14,17H,15-16H2,1-2H3,(H,30,31)/b12-9+
PubChem CID	9936595
ChEMBL	N/A
IUPHAR	1921
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554241	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
554242	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
554239	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
554240	Prostaglandin E2 receptor EP3 subtype	P34980	Ptger3	Rattus norvegicus (Rat)	365

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