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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17418796
Molecular formula	C28H32FN3O5
IUPAC name	(3S)-3-cyclopropyl-3-[3-[[6-(2,2-dimethylpropoxy)-5-(5-fluoro-2-methoxypyridin-4-yl)pyrazin-2-yl]methoxy]phenyl]propanoic acid
Molecular weight	509.578
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	5.0
Synonyms	(3S)-3-Cyclopropyl-3-(3-((5-(5-fluoro-2-methoxypyridin-4-yl)-6-(neopentyloxy)pyrazin-2-yl)methoxy)phenyl)propanoic acid MAFLOYYEUJDHPT-NRFANRHFSA-N BDBM168196 US9688642, 47
Inchi Key	MAFLOYYEUJDHPT-NRFANRHFSA-N
Inchi ID	InChI=1S/C28H32FN3O5/c1-28(2,3)16-37-27-26(22-11-24(35-4)30-14-23(22)29)31-13-19(32-27)15-36-20-7-5-6-18(10-20)21(12-25(33)34)17-8-9-17/h5-7,10-11,13-14,17,21H,8-9,12,15-16H2,1-4H3,(H,33,34)/t21-/m0/s1
PubChem CID	118645574
ChEMBL	N/A
IUPHAR	N/A
BindingDB	168196
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
563612	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300
563613	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300

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