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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL490937
Molecular formula	C19H14F2N4
IUPAC name	2-[5,5-bis(4-fluorophenyl)-1,4-dihydroimidazol-2-yl]pyrazine
Molecular weight	336.346
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.3
Synonyms	BDBM50249738 MGAGGIYVXPYGLM-UHFFFAOYSA-N 4,4-bis(4-fluorophenyl)-2-pyrazinyl-2-imidazoline SCHEMBL4462939 2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyrazine
Inchi Key	MGAGGIYVXPYGLM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H14F2N4/c20-15-5-1-13(2-6-15)19(14-3-7-16(21)8-4-14)12-24-18(25-19)17-11-22-9-10-23-17/h1-11H,12H2,(H,24,25)
PubChem CID	9923839
ChEMBL	CHEMBL490937
IUPHAR	N/A
BindingDB	50249738
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
204564	Neuropeptide Y receptor type 1	P25929	NPY1R	Homo sapiens (Human)	384
204563	Neuropeptide Y receptor type 2	P49146	NPY2R	Homo sapiens (Human)	381
204561	Neuropeptide Y receptor type 4	P50391	NPY4R	Homo sapiens (Human)	375
204562	Neuropeptide Y receptor type 5	Q15761	NPY5R	Homo sapiens (Human)	445

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