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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1773285
Molecular formula	C22H27N5O6S2
IUPAC name	tert-butyl 4-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]sulfonylpiperidine-1-carboxylate
Molecular weight	521.607
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	2.1
Synonyms	BDBM50343441 142924-EP2287165A2 SCHEMBL389524 4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-sulfonyl]-piperidine-1-carboxylic acid tert-butyl ester 142924-EP2287166A2 tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylsulfonyl)piperidine-1-carboxylate 142924-EP2292620A2 [ Show all ]
Inchi Key	NCSITIFSUWIJJL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27N5O6S2/c1-22(2,3)33-21(28)26-11-9-17(10-12-26)35(31,32)20-18-13-25-27(19(18)23-14-24-20)15-5-7-16(8-6-15)34(4,29)30/h5-8,13-14,17H,9-12H2,1-4H3
PubChem CID	21897416
ChEMBL	CHEMBL1773285
IUPHAR	N/A
BindingDB	50343441
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
220130	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468
220131	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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