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Ligand

NameCHEMBL506214
Molecular formulaC20H27N5O2
IUPAC nameN-[(2R)-butan-2-yl]-8-(2,4-dimethoxy-6-methylphenyl)-2,7-dimethylpyrazolo[1,5-a][1,3,5]triazin-4-amine
Molecular weight369.469
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP4.5
SynonymsPyrazolo[1,5-a]-1,3,5-triazine, 12-16
UNII-Q58F5BA91I component OGTPHDYRZSEDNM-GFCCVEGCSA-N
BDBM29447
Inchi KeyOGTPHDYRZSEDNM-GFCCVEGCSA-N
Inchi IDInChI=1S/C20H27N5O2/c1-8-12(3)21-20-23-14(5)22-19-18(13(4)24-25(19)20)17-11(2)9-15(26-6)10-16(17)27-7/h9-10,12H,8H2,1-7H3,(H,21,22,23)/t12-/m1/s1
PubChem CID9820671
ChEMBLCHEMBL506214
IUPHARN/A
BindingDB29447
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 10
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
240929Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
240928Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
240931Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
240927Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
240922Corticotropin-releasing factor receptor 1P35353Crhr1Rattus norvegicus (Rat)415
240925Corticotropin-releasing factor receptor 1P34998CRHR1Homo sapiens (Human)444
240926Corticotropin-releasing factor receptor 2Q13324CRHR2Homo sapiens (Human)411
240923D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
240924D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
240930Vasopressin V1a receptorP37288AVPR1AHomo sapiens (Human)418

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