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Ligand

Name143797-63-1
Molecular formulaC15H14N4O
IUPAC name1-(1-methylindol-5-yl)-3-pyridin-3-ylurea
Molecular weight266.304
Hydrogen bond acceptor2
Hydrogen bond donor2
XlogP1.5
SynonymsNCGC00025128-01
SB-200646 hydrochloride
L000535
PDSP2_001620
SCHEMBL173735
[ Show all ]
Inchi KeyOJZZJTLBYXHUSJ-UHFFFAOYSA-N
Inchi IDInChI=1S/C15H14N4O/c1-19-8-6-11-9-12(4-5-14(11)19)17-15(20)18-13-3-2-7-16-10-13/h2-10H,1H3,(H2,17,18,20)
PubChem CID126769
ChEMBLCHEMBL85194
IUPHARN/A
BindingDB82272
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 16
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
2432945-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
2432915-hydroxytryptamine receptor 1DQ60484HTR1DCavia porcellus (Guinea pig)376
2432905-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
2432935-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
2432885-hydroxytryptamine receptor 2BP30994Htr2bRattus norvegicus (Rat)479
2432965-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
2432855-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
2432865-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
2432895-hydroxytryptamine receptor 2CP34968Htr2cMus musculus (Mouse)459
243295Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
243298Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
243297Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
243287Beta-1 adrenergic receptorP18090Adrb1Rattus norvegicus (Rat)466
461311Beta-2 adrenergic receptorP10608Adrb2Rattus norvegicus (Rat)418
243292D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
556422D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443

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