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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL370596
Molecular formula	C27H28FN3O2
IUPAC name	N-[3-[(E)-3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-3-oxoprop-1-enyl]naphthalen-2-yl]acetamide
Molecular weight	445.538
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.1
Synonyms	OKPDPHQVVCXCIO-VSRDTVRMSA-N SCHEMBL3164677 BDBM50174706 N-(3[(E)-3-[(R)-4-(4-Fluorobenzyl)-2-methylpiperazin-1-yl]-3-oxopropenyl]-naphthalen-2-yl)-acetamide (R)-N-(3-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)naphthalen-2-yl)acetamide
Inchi Key	OKPDPHQVVCXCIO-VSRDTVRMSA-N
Inchi ID	InChI=1S/C27H28FN3O2/c1-19-17-30(18-21-7-10-25(28)11-8-21)13-14-31(19)27(33)12-9-24-15-22-5-3-4-6-23(22)16-26(24)29-20(2)32/h3-12,15-16,19H,13-14,17-18H2,1-2H3,(H,29,32)/b12-9+/t19-/m1/s1
PubChem CID	10388824
ChEMBL	CHEMBL370596
IUPHAR	N/A
BindingDB	50174706
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
243801	C-C chemokine receptor type 1	P32246	CCR1	Homo sapiens (Human)	355
243802	C-C chemokine receptor type 1	P51675	Ccr1	Mus musculus (Mouse)	355

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