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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	6-HYDROXYMELATONIN
Molecular formula	C13H16N2O3
IUPAC name	N-[2-(6-hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide
Molecular weight	248.282
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	1.2
Synonyms	CHEMBL127421 H 0627 L024000 MFCD00037971 NCGC00015495-04 PDSP2_001795 UNII-TV437T5077 2208-41-5 6-OH-MLT AKOS022663797 D0S6SN HMS3261L06 LP00612 N-[2-(6-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide NCGC00261297-01 SMR000326915 6-hydroxy melatonin Acetamide, N-(2-(6-hydroxy-5-methoxy-1H-indol-3-yl)ethyl)- C05643 FT-0669728 J-014482 Melatonin, 6-hydroxy- NCGC00015495-02 PDSP1_001812 Tox21_500612 0733A77F-D227-41FD-853E-28134CB5AC46 6-Hydroxymelatonine Acetamide, N-[2-(6-hydroxy-5-methoxy-1H-indol-3-yl)ethyl]- CHEBI:2198 CS-W012672 H-6490 Lopac-H-0627 MLS000860057 NCGC00093987-01 SCHEMBL674970 ZINC57344 3-(N-Acetylaminoethyl)-6-hydroxy-5-methoxyindole BDBM82509 DTXSID00176577 HMS3370G03 LS-9709 N-[2-(6-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide # OMYMRCXOJJZYKE-UHFFFAOYSA-N SR-01000075901 6-Hydroxy-N-acetyl-5-methoxytryptamine Acetamide, N-(2-(6-hydroxy-5-methoxy-1H-indol-3-yl)ethyl)- (9CI) CCG-204701 GTPL1347 KB-178583 Melatonin,6-Hydroxy NCGC00015495-03 PDSP2_001770 TV437T5077 6-OH-melatonin Acetamide, N-[2-(6-hydroxy-5-methoxyindol-3-yl)ethyl]- CTK8F7147 HMS2231I10 Lopac0_000612 N-(2-(6-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl)acetamide NCGC00093987-02 SCHEMBL674971 5-22-12-00353 (Beilstein Handbook Reference) AC1L1CEL BRN 0483231 EU-0100612 HY-W011956 melatonin, 6-Hydroxy NCGC00015495-01 PDSP1_001787 SR-01000075901-1 ACETAMIDE, N-(2-(6-HYDROXY-5-METHOXYINDOL-3-YL)ETHYL)- CCRIS 3473 [ Show all ]
Inchi Key	OMYMRCXOJJZYKE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H16N2O3/c1-8(16)14-4-3-9-7-15-11-6-12(17)13(18-2)5-10(9)11/h5-7,15,17H,3-4H2,1-2H3,(H,14,16)
PubChem CID	1864
ChEMBL	CHEMBL127421
IUPHAR	1347
BindingDB	82509
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
245399	Melatonin receptor type 1A	O02781	MTNR1A	Sus scrofa (Pig)	154
245401	Melatonin receptor type 1A	P48039	MTNR1A	Homo sapiens (Human)	350
245402	Melatonin receptor type 1A	P48040	MTNR1A	Ovis aries (Sheep)	366
245398	Melatonin receptor type 1B	P49286	MTNR1B	Homo sapiens (Human)	362
245400	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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