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Ligand

NameCHEMBL411315
Molecular formulaC20H14Cl2N2O5
IUPAC name2-[(3R)-5-chloro-1'-[(3-chlorophenyl)methyl]-2,2',5'-trioxospiro[indole-3,3'-pyrrolidine]-1-yl]acetic acid
Molecular weight433.241
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP2.3
SynonymsSpiro-indolinone analogue, (R)-60
BDBM21605
SCHEMBL2483382
2-[(3R)-5-chloro-1''-[(3-chlorophenyl)methyl]-1,2-dihydrospiro[indole-3,3''-pyrrolidine]-2,2'',5''-trione]acetic acid
Inchi KeyPTGHDUZXAIHWGN-HXUWFJFHSA-N
Inchi IDInChI=1S/C20H14Cl2N2O5/c21-12-3-1-2-11(6-12)9-24-16(25)8-20(19(24)29)14-7-13(22)4-5-15(14)23(18(20)28)10-17(26)27/h1-7H,8-10H2,(H,26,27)/t20-/m1/s1
PubChem CID15949677
ChEMBLCHEMBL411315
IUPHARN/A
BindingDB21605
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 4
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
268321Prostaglandin D2 receptorQ13258PTGDRHomo sapiens (Human)359
268318Prostaglandin D2 receptor 2Q9Y5Y4PTGDR2Homo sapiens (Human)395
268319Prostaglandin D2 receptor 2Q9Z2J6Ptgdr2Mus musculus (Mouse)382
268320Prostaglandin E2 receptor EP2 subtypeP43116PTGER2Homo sapiens (Human)358

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