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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL411315
Molecular formula	C20H14Cl2N2O5
IUPAC name	2-[(3R)-5-chloro-1'-[(3-chlorophenyl)methyl]-2,2',5'-trioxospiro[indole-3,3'-pyrrolidine]-1-yl]acetic acid
Molecular weight	433.241
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.3
Synonyms	2-[(3R)-5-chloro-1''-[(3-chlorophenyl)methyl]-1,2-dihydrospiro[indole-3,3''-pyrrolidine]-2,2'',5''-trione]acetic acid Spiro-indolinone analogue, (R)-60 BDBM21605 SCHEMBL2483382
Inchi Key	PTGHDUZXAIHWGN-HXUWFJFHSA-N
Inchi ID	InChI=1S/C20H14Cl2N2O5/c21-12-3-1-2-11(6-12)9-24-16(25)8-20(19(24)29)14-7-13(22)4-5-15(14)23(18(20)28)10-17(26)27/h1-7H,8-10H2,(H,26,27)/t20-/m1/s1
PubChem CID	15949677
ChEMBL	CHEMBL411315
IUPHAR	N/A
BindingDB	21605
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
268321	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
268318	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
268319	Prostaglandin D2 receptor 2	Q9Z2J6	Ptgdr2	Mus musculus (Mouse)	382
268320	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358

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