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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	20-Hydroxy-leukotriene B4
Molecular formula	C20H32O5
IUPAC name	(5S,6Z,8E,10E,12R,14Z)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoic acid
Molecular weight	352.471
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	2.5
Synonyms	(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-Trihydroxyicosa-6,8,10,14-tetraenoic acid 20-OH-5S,12S-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid 6,8,10,14-Eicosatetraenoic acid, 5,12,20-trihydroxy-, (5S,6Z,8E,10E,12R,14Z)- CHEBI:15646 omega-Hydroxy-LTB4 (5S,12R)-5,12,20-Trihydroxy-(6Z,8E,10E,14Z)-eicosatetraenoic acid 20-hydroxy LTB4 AC1NQXIZ GTPL3399 SR-01000946893-1 (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-Trihydroxyeicosa-6,8,10,14-tetraenoic acid 20-hydroxyleukotriene B4 5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoate BML1-E05 LTB4_20-Hydroxy [S-[R,S-(E,Z,E,Z)]]-5,12,20-trihydroxy-6,8,10,14-Eicosatetraenoate 1075AH 20-OH-Leukotriene B4 79516-82-8 CHEMBL1593789 SCHEMBL142275 (5S,6Z,8E,10E,12R,14Z)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoic acid 5,12,20-THETE AKOS027378121 LMFA03020018 w-Hydroxy-LTB4 (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-Trihydroxyicosa-6,8,10,14-tetraenoate 20-OH-5S,12S-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate 5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid C04853 NCGC00161274-01 [S-[R,S-(E,Z,E,Z)]]-5,12,20-trihydroxy-6,8,10,14-Eicosatetraenoic acid (5S,12R)-5,12,20-Trihydroxy-(6Z,8E,10E,14Z)-eicosatetraenoate 20-hydroxy Leukotriene B4 20-OH-LTB4 D0I4FF SR-01000946893 (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-Trihydroxyeicosa-6,8,10,14-tetraenoate 20-hydroxy-LTB4 5,12,20-Trihete BDBM85696 LTB4-20-hydroxy ZINC4629872 [ Show all ]
Inchi Key	PTJFJXLGRSTECQ-PSPARDEHSA-N
Inchi ID	InChI=1S/C20H32O5/c21-17-10-6-2-1-3-7-12-18(22)13-8-4-5-9-14-19(23)15-11-16-20(24)25/h3-5,7-9,13-14,18-19,21-23H,1-2,6,10-12,15-17H2,(H,24,25)/b5-4+,7-3-,13-8+,14-9-/t18-,19-/m1/s1
PubChem CID	5280745
ChEMBL	N/A
IUPHAR	3399
BindingDB	85696
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554594	Leukotriene B4 receptor 1	Q15722	LTB4R	Homo sapiens (Human)	352
461539	Leukotriene B4 receptor 2	Q9NPC1	LTB4R2	Homo sapiens (Human)	358

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