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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL27254
Molecular formula	C22H28IN3O2
IUPAC name	4-iodo-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Molecular weight	493.389
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.2
Synonyms	BDBM50007179 N-[4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl]-4-iodobenzamide 4-Iodo-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide
Inchi Key	PZTFOAIQGVVNAX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28IN3O2/c1-28-21-7-3-2-6-20(21)26-16-14-25(15-17-26)13-5-4-12-24-22(27)18-8-10-19(23)11-9-18/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,27)
PubChem CID	10368423
ChEMBL	CHEMBL27254
IUPHAR	N/A
BindingDB	50007179
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
272946	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
272948	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
272947	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
272949	D(3) dopamine receptor	P52703	DRD3	Chlorocebus aethiops (Green monkey)	400

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