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Ligand

NameSkf-77434
Molecular formulaC19H21NO2
IUPAC name5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol
Molecular weight295.382
Hydrogen bond acceptor3
Hydrogen bond donor2
XlogP3.6
Synonyms(+/-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride
BDBM50004918
L001232
PDSP1_001525
[ Show all ]
Inchi KeyQBUVZVXIRYFENV-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2
PubChem CID1241
ChEMBLCHEMBL288090
IUPHARN/A
BindingDB50004918
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
2744645-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
5565385-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
2744625-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
274468Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
274461D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
274463D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
274465D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
274467D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
274466D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400

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