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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL6933222
Molecular formula	C27H37N3O3
IUPAC name	N-(2-methoxyphenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]cyclohexanecarboxamide
Molecular weight	451.611
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.9
Synonyms	BDBM86709 Rec 27/0074
Inchi Key	QQLBAAQRZXVWPZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H37N3O3/c1-32-25-14-8-6-12-23(25)29-19-16-28(17-20-29)18-21-30(24-13-7-9-15-26(24)33-2)27(31)22-10-4-3-5-11-22/h6-9,12-15,22H,3-5,10-11,16-21H2,1-2H3
PubChem CID	9868460
ChEMBL	N/A
IUPHAR	N/A
BindingDB	86709
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
284462	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
556586	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
284459	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
284460	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
284461	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
556587	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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