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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL273953
Molecular formula	C14H12N4O4
IUPAC name	3-(1,3-dimethyl-2,6-dioxo-7H-purin-8-yl)benzoic acid
Molecular weight	300.274
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	1.7
Synonyms	BDBM50020851 3-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzoic acid
Inchi Key	QRGYKGMTLSMLOI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H12N4O4/c1-17-11-9(12(19)18(2)14(17)22)15-10(16-11)7-4-3-5-8(6-7)13(20)21/h3-6H,1-2H3,(H,15,16)(H,20,21)
PubChem CID	13525048
ChEMBL	CHEMBL273953
IUPHAR	N/A
BindingDB	50020851
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
285024	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
285026	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
285023	Adenosine receptor A2a	P46616	ADORA2A	Cavia porcellus (Guinea pig)	409
285025	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332

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