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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	G-36
Molecular formula	C22H22BrNO2
IUPAC name	(3aS,4R,9bR)-4-(6-bromo-1,3-benzodioxol-5-yl)-8-propan-2-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
Molecular weight	412.327
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.0
Synonyms	D06CAL (3aS)-4alpha-(6-Bromo-1,3-benzodioxole-5-yl)-8-isopropyl-3abeta,4,5,9bbeta-tetrahydro-3H-cyclopenta[c]quinoline GTPL6480 (3aS,4R,9bR)-4-(6-bromo-2H-1,3-benzodioxol-5-yl)-8-(propan-2-yl)-3H,3aH,4H,5H,9bH-cyclopenta[c]quinoline MolPort-035-765-825 AKOS024458333 (+/-)-(3aR,4S,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline G36 1392487-51-2 ZINC36082348 [ Show all ]
Inchi Key	QTOCPACSSHFGOY-ZCCHDVMBSA-N
Inchi ID	InChI=1S/C22H22BrNO2/c1-12(2)13-6-7-19-16(8-13)14-4-3-5-15(14)22(24-19)17-9-20-21(10-18(17)23)26-11-25-20/h3-4,6-10,12,14-15,22,24H,5,11H2,1-2H3/t14-,15+,22-/m1/s1
PubChem CID	73755224
ChEMBL	N/A
IUPHAR	6480
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554693	G-protein coupled estrogen receptor 1	Q99527	GPER1	Homo sapiens (Human)	375

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