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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	zaprinast
Molecular formula	C13H13N5O2
IUPAC name	5-(2-propoxyphenyl)-2,6-dihydrotriazolo[4,5-d]pyrimidin-7-one
Molecular weight	271.28
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	1.6
Synonyms	SR-01000597480-1 Zaprinast (M&B 22948) AC1L1KZQ NCGC00016105-05 BCBcMAP01_000103 NCGC00261925-01 BSPBio_001348 Prestwick3_000335 SPBio_001313 DSSTox_RID_80761 HMS1791D10 1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one HMS3370J04 2-(o-Propoxyphenyl)-8-azapurin-6-one KBio2_004313 3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one LS-156833 5-(2-propoxyphenyl)-3,6-dihydrotriazolo[4,5-d]pyrimidin-7-one MLS000859963 SR-01000075536 Tox21_110306_1 Zaprinast, solid MolPort-004-964-803 AKOS024458708 NCGC00024894-03 BRD-K12516989-001-01-9 NSC757885 CCG-205314 SBI-0051207.P002 CTK8G3814 Spectrum2_001447 EU-0101240 HMS2090L04 HMS501N06 2103AH KBioGR_001583 5-(2-Propoxyphenyl)-1H-[1,2,3]triazolo[4,5-d]pyrimidin-7(4H)-one M&B 22,948 6,7-Dihydro-5-(2-propoxyphenyl)-1H-triazolo(4,5-d)pyrimidin-7-on SR-01000075536-5 Z 0878 ZINC14953365 NCGC00016105-03 API0000888 NCGC00094481-01 BS0209 Prestwick1_000335 CCG-39177 SMP1_000321 DSSTox_CID_25224 Spectrum5_001023 GXT25D5DS0 1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one HMS3263H22 2-(2-propoxyphenyl)-8-azapurin-6-one KBio1_000584 3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one Lopac0_001240 5-(2-propoxyphenyl)-2,3-dihydrotriazolo[4,5-e]pyrimidin-7-one M&B22948 8-Aza-2-(2-propoxyphenyl)-6-purinone Tocris-0947 Zaprinast [BAN:INN] AC1Q6AZY NCGC00024894-01 BDBM14363 NINDS_000584 C13H13N5O2 Prestwick_655 CHEMBL28079 SPBio_002290 DTXSID8045224 HMS1921P15 1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one HMS3402D10 2-o-Propoxyphenyl-8-azapurin-6-on KBio2_006881 37762-06-4 M & B 22948 5-(2-propoxyphenyl)-3H,4H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one MolPort-003-666-387 SR-01000075536-1 Tox21_501240 Zaprinastum NCGC00016105-01 AKOS027446368 NCGC00024894-04 BRD-K16542329-001-05-1 Pharmakon1600-01501199 CCG-220335 SCHEMBL50328 D00YPW Spectrum3_000933 FT-0675894 HMS2096C11 2-(2-Propoxyphenyl)-8-aza-6-purinone IDI1_000584 KBioSS_001745 5-(2-propoxyphenyl)-1h-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol M&B 22948 6,7-Dihydro-5-(2-propoxyphenyl)-1H-triazolo(4,5-d)pyrimidin-7-on [IUPAC] SR-01000597480 AB00052245_02 NCGC00016105-04 B6516 NCGC00094481-02 BSPBio_000369 Prestwick2_000335 CHEBI:92215 SMR000326822 DSSTox_GSID_45224 Spectrum_001265 HMS1569C11 1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one HMS3267G07 2-(2-Propyloxyphenyl)-8-azapurin-6-one KBio2_001745 3,6-Dihydro-5-(o-propoxyphenyl)-7H-v-triazolo(4,5-d)pyrimidin-7-one LP01240 5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one MFCD00214073 Tox21_110306 Zaprinast [INN:BAN] ACM37762064 NCGC00024894-02 BPBio1_000407 NSC-757885 CAS-37762-06-4 REZGGXNDEMKIQB-UHFFFAOYSA-N CTK5A3076 SPECTRUM1501199 EINECS 253-655-1 HMS1989D10 1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5d]pyrimidine-7-one HMS3713C11 2-o-Propoxyphenyl-8-azapurine-6-one KBio3_001966 5-(2-Propoxy-phenyl)-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one M and B 22948 55122-20-8 MolPort-003-983-815 SR-01000075536-4 UNII-GXT25D5DS0 Zaprinastum [INN-Latin] NCGC00016105-02 AOB5951 NCGC00024894-08 BRD-K16542329-001-08-5 Prestwick0_000335 CCG-222544 SCHEMBL6913739 DivK1c_000584 Spectrum4_001032 GTPL2919 1,4-Dihydro-5-(2-propoxyphenyl)-1,2,3-triazolo(4,5-d)pyrimidin-7-one HMS2235N23 2-(2-propoxyphenyl)-8-azahypoxanthine IN1012 3,6-Dihydro-5-(2-propoxyphenyl)-7H-(1,2,3)truaziki(4,5-d)pyrimidin-7-on Lopac-Z-0878 5-(2-propoxyphenyl)-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one M&B-22948 7H-1,2,3-Triazolo(4,5-d)pyrimidin-7-one, 1,4-dihydro-5-(2-propoxyphenyl)- [ Show all ]
Inchi Key	REZGGXNDEMKIQB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H13N5O2/c1-2-7-20-9-6-4-3-5-8(9)11-14-12-10(13(19)15-11)16-18-17-12/h3-6H,2,7H2,1H3,(H2,14,15,16,17,18,19)
PubChem CID	135399235
ChEMBL	CHEMBL28079
IUPHAR	2919
BindingDB	14363
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
294554	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
294555	G-protein coupled receptor 35	Q9ES90	Gpr35	Mus musculus (Mouse)	307

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