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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Fluspiperone
Molecular formula	C23H25F2N3O2
IUPAC name	1-(4-fluorophenyl)-8-[4-(4-fluorophenyl)-4-oxobutyl]-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight	413.469
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.1
Synonyms	1,3,8-Triazaspiro(4.5)decan-4-one, 1-(4-fluorophenyl)-8-(4-(4-fluorophenyl)-4-oxobutyl)- 8-[3-(p-Fluorobenzoyl)propyl]-1-(p-fluorophenyl)-1,8-triazaspiro[4.5]decan-4-one CTK5A2851 NSC-354855 UNII-V0Q53N427T 1-(4-fluorophenyl)-8-[4-(4-fluorophenyl)-4-oxobutyl]-1,3,8-triazaspiro[4.5]decan-4-one AC1Q4NKH PDSP1_000980 {1,3,8-Triazaspiro[4.5]decan-4-one,} {1-(4-fluorophenyl)-8-[4-(4-fluorophenyl)-4-oxobutyl]-} 54965-22-9 CAS_54965-22-9 L000948 R-28930 1,8-Triazaspiro[4.5]decan-4-one, 1-(4-fluorophenyl)-8-[4-(4-fluorophenyl)-4-oxobutyl]- D02661 NSC354855 V0Q53N427T 4-(4-fluorophenyl)-8-[4-(4-fluorophenyl)-4-oxo-butyl]-2,4,8-triazaspiro[4.5]decan-1-one AKOS030574103 Fluspiperone (USAN/INN) PDSP2_000964 {8-[3-(p-Fluorobenzoyl)propyl]-1-(p-fluorophenyl)-1,3,} {8-triazaspiro[4.5]decan-4-one} 8-(3-(p-Fluorobenzoyl)propyl)-1-(p-fluorophenyl)-1,3,8-triazaspiro(4.5)decan-4-one CHEMBL2104750 NSC 354855 SCHEMBL121266 1-(4-Fluorophenyl)-8-(4-(4-fluorophenyl)-4-oxobutyl)-1,3,8-triazaspiro[4.5]decan-4-one AC1L4Y9O DTXSID20203495 NSC_166535 ZINC537753 4-(4-fluorophenyl)-8-[4-(4-fluorophenyl)-4-oxobutyl]-2,4,8-triazaspiro[4.5]decan-1-one BDBM85032 Fluspiperone [USAN:INN] R 28,930 [ Show all ]
Inchi Key	RIOZXKPJYKSKJV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25F2N3O2/c24-18-5-3-17(4-6-18)21(29)2-1-13-27-14-11-23(12-15-27)22(30)26-16-28(23)20-9-7-19(25)8-10-20/h3-10H,1-2,11-16H2,(H,26,30)
PubChem CID	166535
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85032
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
297050	5-hydroxytryptamine receptor 7	P32304	Htr7	Mus musculus (Mouse)	448

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