Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	3-Chloro-5-hydroxybenzoic acid
Molecular formula	C7H5ClO3
IUPAC name	3-chloro-5-hydroxybenzoic acid
Molecular weight	172.564
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	1.8
Synonyms	FT-0080917 RJOLIYHZZKAIET-UHFFFAOYSA-N X8059 3-hydroxy-5-chlorobenzoic acid ACMC-209lbs Benzoic acid, 3-chloro-5-hydroxy- K-9757 SCHEMBL1999585 53984-36-4 AKOS006293910 CHEMBL2146910 DB-006403 MFCD04114327 TC-120655 AB0033979 ANW-31910 FT-0650742 SBB052708 ZINC2599133 4CH-024347 AJ-43876 Benzoic acid,3-chloro-5-hydroxy- CL8082 KB-31117 ST24042056 3-chloranyl-5-oxidanyl-benzoic acid 984C364 AM84171 DTXSID50517335 MolPort-009-196-828 TS-02354 3-Chloro-5-hydroxybenzoic acid, >=97% (HPLC) AB18080 BDBM50391825 I01-11521 SC-73033 AK107678 CTK4J9210 KS-00000K5A SY025109 3-CHLORO-5-HYDROXY-BENZOIC ACID A829885 AN-40681 [ Show all ]
Inchi Key	RJOLIYHZZKAIET-UHFFFAOYSA-N
Inchi ID	InChI=1S/C7H5ClO3/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,9H,(H,10,11)
PubChem CID	13071646
ChEMBL	CHEMBL2146910
IUPHAR	N/A
BindingDB	50391825
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
297794	Hydroxycarboxylic acid receptor 1	Q8C131	Hcar1	Mus musculus (Mouse)	343
297795	Hydroxycarboxylic acid receptor 1	Q9BXC0	HCAR1	Homo sapiens (Human)	346
297796	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218